The New York State Department of Health is urging residents to receive the 2025-2026 seasonal influenza vaccine after new federal data revealed a rise in severe flu-related complications among children. According to the U.S. Centers for Disease Control and Prevention (CDC), the most recent Morbidity and Mortality Weekly Report found 109 cases of influenza-associated encephalopathy (IAE) in children across the United States during the 2024-25 flu season, with 37 of those cases classified as acute necrotizing encephalopathy (ANE), a rare but serious condition.
“The seasonal flu vaccine is the best way to protect against these tragedies and is the best measure of protection for babies and young children who are vulnerable to severe pediatric-related illnesses caused by the flu,” said State Health Commissioner Dr. James McDonald. “As we head into the respiratory season this fall, the 2025-2026 flu vaccine is widely available. I encourage all New Yorkers to either make an appointment with a provider or stop by your local pharmacy to get vaccinated and enjoy the peace of mind that you and your family and loved ones are protected.”
State data shows an upward trend in pediatric flu deaths over recent years: three deaths were reported in the 2021-22 season, rising to 14 in 2022-23, and reaching 20 deaths in the 2023-24 season.
The Department emphasizes that vaccination remains the most effective way to prevent serious illness or death from influenza. Pharmacies across New York provide flu vaccines without a prescription for individuals aged two and older, while children six months and older can be vaccinated at healthcare providers’ offices.
Further details about influenza vaccines can be found on the Department’s website, and information regarding vaccine safety is available here.



